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985 inborn infants who would reach 40 weeks post-conceptional age between January 7, 1985 and October 9, 1985 and whose birth weights were less than or equal to 2500g and met criteria related primarily to residence, gestational age, and hospital discharge before recruitment period. (Unhealthy infants were included unless they had an illness so severe as to preclude intervention in the program).
Subjects were categorized into 2 weight groups: >2000g=”heavier” (N=362)and <2000g=”lighter” (N=623). Random assignment to the intervention or follow-up within each group resulted in 220 heavier infants were assigned to follow-up and 142 to intervention. In the lighter group, 388 were assigned to follow-up and 235 to intervention.
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